Studies on Starling's Law of the Heart Determinants of the Relationship Between Left Ventricular End-Diastolic Pressure and Circumference
نویسندگان
چکیده
IN EXPERIMENTS oti the dog heart-lung preparation which led to the formulation of the well-known "Law of the Heart," Patterson, Piper and Starling observed that when cardiac work was augmented, ventricular volume sometimes increased in the face of a constant left ventricular end-diastolic pressure. These investigators concluded that the strength of myocardial contraction was a function of end-diastolic fiber length.Although this view is supported by the experiments of Kozawa, other investigators have concluded that the initial intraventricular tension" or both the end-diastolic fiber length and the initial tension" are responsible for the characteristics of the subsequent contraction.
منابع مشابه
Studies on Starling's Law of the Heart. Iii. Observations in Patients with Mitral Stenosis and Atrial Fibrillation on the Relationships between Left Ventricular End-diastolic Segment Length, Filling Pressure, and the Characteristics of Ventricular Contraction.
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